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KMID : 0360120090310030249
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Journal of the Korean Society of Maxillofacial Plastic Reconstructive Surgeons
2009 Volume.31 No. 3 p.249 ~ p.253
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Use of corticosteroids in the treatment of Localized Langerhans cell histiocytosis of the mandible
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Choi Jung-Yong
Lee Sang-Hwa
Yoon Hyun-Joong
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Abstract
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Langerhans cell histiocytosis(LCH), previously known as histiocytosis X, is rare, proliferative disorder in which the accumulation of pathologic Langerhans cell leads to tissue infiltration and destruction. The jaw is involved 10~20% of all LCH and most common oral symptoms are jaw swelling or a palpation mass. Most of subjects are males and disease appears to start before the age of 10 years. An 11 years old girl was referred from pediatric department. Histological examination confirmed the diagnosis LCH. She was treated intra-lesional injection of corticosteroid. The overall outcome was excellent. After a follow-up period of 20 month, the patient present with no evidence of residual disease on Panoramic view and whole body bone scan. We report this early recognized LCH case treated by corticoid injection in good progress with literature review.
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KEYWORD
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Langerhans cell histiocytosis, Eosinophilic granuloma, Corticosteroids, Intralesional injection
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